Coagulopathy in Head Trauma – as Complicated as Ever

نویسنده

  • N Scott Litofsky
چکیده

Many years ago, while I was a Chief Resident in my neurological surgery training program, I solicited the aid of my Department Chairman to have the Emergency Department add coagulation testing to the routine labs acquired on head trauma patients. Believe it or not, at that time, despite knowledge that coagulopathy frequently complicates traumatic brain injury (TBI), such testing was usually not performed until the neurosurgery service ordered the test. While understanding about coagulation deficits has increased over time, the problem has also become increasingly complicated by an older population, additional causes of coagulopathy (particularly in the form of new drugs), additional tests to define coagulopathy, and new (and expensive potential treatments).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Severity of head injury is associated with increased risk of coagulopathy in combat casualties.

BACKGROUND Traumatic brain injury (TBI) is believed to cause more profound trauma-induced coagulopathy than other injuries of comparable severity. This has not been reported in a large series of combat casualties in which penetrating injuries predominate. METHODS Among US combat casualties severely injured in Iraq and Afghanistan who received transfused blood products, isolated TBI patients (...

متن کامل

ارزیابی نشانگرهای انعقادی در بیماران آسیب مغزی، بیمارستان امام رضا (ع) بیرجند، سال 1385

  Background and Aim: Coagulopathy is a common phenomenon in brain trauma that affects the prognosis of the patients. This study aimed at evaluating the coagulation markers and its association with prognosis in patients with brain injury.   Materials and Methods: This descriptive-analytical study was performed on 42 patients with head trauma with GCS ≤ 10 in Imam Reza Hospital of Birjand in ...

متن کامل

Trauma-induced coagulopathy: standard coagulation tests, biomarkers of coagulopathy, and endothelial damage in patients with traumatic brain injury.

It remains to be debated whether traumatic brain injury (TBI) induces a different coagulopathy than does non-TBI. This study investigated traditional coagulation tests, biomarkers of coagulopathy, and endothelial damage in trauma patients with and without TBI. Blood from 80 adult trauma patients was sampled (median of 68 min [IQR 48-88] post-injury) upon admission to our trauma center. Plasma/s...

متن کامل

Coagulopathy in trauma patients: what are the main influence factors?

PURPOSE OF REVIEW Coagulopathy and bleeding after severe injury is a common problem. Whenever caring for critically ill patients, clinicians must anticipate, recognize and manage the coagulopathy of trauma. When left untreated, cardiovascular shock and multiorgan system failure ensue. Uncompensated hemorrhage often culminates in death, highlighting the significance of recognizing the main influ...

متن کامل

The coagulopathy of trauma: a review of mechanisms.

BACKGROUND Bleeding is the most frequent cause of preventable death after severe injury. Coagulopathy associated with severe injury complicates the control of bleeding and is associated with increased morbidity and mortality in trauma patients. The causes and mechanisms are multiple and yet to be clearly defined. METHODS Articles addressing the causes and consequences of trauma-associated coa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016